BDBM50061881 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmethyl-8-aza-bicyclo[3.2.1]octane::CHEMBL440272

SMILES Fc1ccc(cc1)C(OC1CC2CCC(C1)N2CC1CC1)c1ccc(F)cc1

InChI Key InChIKey=PMCPPYXVCCGLLE-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061881   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  1.19E+3nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain SERT after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed